Spectroscopic and Spectrometric Analysis Laboratory
MEASUREMENTS USING THE NMR
- identification of molecular and macromolecular substances in solutions, homogenates and solid body,
- determining of chemical compound structure – chiefly organic, coordinative and bio particles,
- qualitative and quantitative determining of organic compounds,
- observation of dynamic particle transformations,
- following the reaction progress,
- variable temperature measurements
- proteomics: determining of protein structure, determining of reacting between proteins and small particles,
- metabolomic profiling,
- pharmacology: identification and purity of active pharmaceutical substances.
The Laboratory performs the qualitative and quantitative analysis with determining the structure of chemical compounds in the scope of:
- Proteomics: peptide analysis with the “bottom up” method and fragmentation type CID, HCD and ETD in order to identify proteins, post translation modification analysis (phosphorylation and glycosylation), peptide quantitative analysis (SRM/MRM), de novo proteins identification, “top down” method protein analysis
- Metabolomics: profiling and identification of metabolites in clinical samples (serum, urine) and tissue material, analysis of low molecular weight substances
- Lipidomics: separation and identification of lipids and derived compounds, profiling of cell and membrane lipids of plant, animal and human origin, quantitative analysis
- Pharmacokinetics: DMPK analysis of medicines and their derivates in physiological liquids (serum, urine), test of medicines and cosmetics components, identification and structure determination of medicines and dietary supplements
- MALDI Imaging: identification and analysis of protein and metabolites distribution in tissues
- MALDI Biotyper: an innovative method of identification of microorganisms in biological materials (bacteria, yeasts, fungi)

Łukasiewicz – PORT Polish Center for Technology Development
SPECTROMETER NMR AVANCE III HD 500 MHZ (BRUKER)
cross section measurements in solutions, changer for 60 samples, provided with probes: BBI and BBO
SPECTROMETER NMR AVANCE III HD 600 MHZ (BRUKER)
measurements in solutions (changer for 16 samples) as well as in a solid body and homogenates, provided with probes: BBFO, CP MAS 1.3 and 3.2 mm and HR MAS 4 mm
SPECTROMETER NMR AVANCE III HD 700 MHZ (BRUKER)
measurements in solutions using a cryoprobe QCI, changer for 24 samples, additionally provided with probes: BBO, TXI (P and N) All the spectrometers are provided with attachments for variable temperature measurements. The Laboratory has a dedicated room for sample storage.
Ultra-high resolution, hybrid mass spectrometer with Fourier’s transformation LTQ Orbitrap Elite (Thermo Scientific)
- mass analysers: LTQ (linear ion trap), high field Orbitrap
- exchangeable ion sources: ESI (HESI), APCI and Nano
- fragmentation CID, PQD, HCD and ETD
- ion mobility FAIMS module
- liquid chromatograph Easy nano-LC 1000 and Ultimate 3000
High resolution mass spectrometer QTOF Maxis Impact (Bruker)
- mass analysers: quadrupole and time of flight analyser
- exchangeable ion sources: ESI, APCI and nano CaptiveSpray
- fragmentation: CID
- ultra high-performance liquid chromatograph Ultimate 3000 (Thermo Fisher Scientific) Ultimate 3000 (Thermo Fisher Scientific)
High resolution mass spectrometer ultrafleXtreme MALDI TOF/TOF (Bruker)
- Biotyper for microorganism identification (bacteria, fungi)
- ImagePrep for tissue analysis with the MALDI imaging method
- fragmentation: CID, LIFT
- Proteineer fc II automatic robot
- liquid chromatograph Easy nLC (Bruker)
Mass spectrometer LTQ (Thermo Scientific)
- mass analyser: LTQ (linear ion trap)
- ion source: ESI
- fragmentation CID
- ultra high-performance liquid chromatograph Ultimate 3000 (Thermo Fisher Scientific) Ultimate 3000 (Thermo Fisher Scientific)

Łukasiewicz – PORT Polish Center for Technology Development