{"id":93081,"date":"2025-04-17T10:25:28","date_gmt":"2025-04-17T08:25:28","guid":{"rendered":"https:\/\/port.lukasiewicz.gov.pl\/?post_type=projects&#038;p=93081"},"modified":"2025-12-16T18:52:30","modified_gmt":"2025-12-16T17:52:30","slug":"development-of-a-novel-aptamer-based-therapeutic-method-for-melanoma-mat","status":"publish","type":"projects","link":"https:\/\/port.lukasiewicz.gov.pl\/en\/projekty-badawcze\/development-of-a-novel-aptamer-based-therapeutic-method-for-melanoma-mat\/","title":{"rendered":"Development of a Novel Aptamer-Based Therapeutic Method for Melanoma \u2013 MAT"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"93081\" class=\"elementor elementor-93081 elementor-67895\" data-elementor-post-type=\"projects\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0739833 e-flex e-con-boxed e-con e-parent\" data-id=\"0739833\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-197a220 elementor-widget elementor-widget-text-editor\" data-id=\"197a220\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"0\" data-end=\"125\">Project funded by the National Centre for Research and Development under the Smart Growth Operational Programme 2014\u20132020<\/p><p data-start=\"127\" data-end=\"300\">Priority Axis IV: Increasing the Scientific and Research Potential<br data-start=\"193\" data-end=\"196\" \/>Action 4.1: Research and Development<br data-start=\"232\" data-end=\"235\" \/>Sub-action 4.1.1: \u201cStrategic Research Programmes for the Economy\u201d<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c506a98 e-flex e-con-boxed e-con e-parent\" data-id=\"c506a98\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-b412081 e-con-full cut-off-wrapper-90 e-flex e-con e-child\" data-id=\"b412081\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-11da8ac elementor-widget elementor-widget-text-editor\" data-id=\"11da8ac\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Project value: <strong data-start=\"317\" data-end=\"337\">PLN 2,354,428.75<\/strong> (including <strong data-start=\"349\" data-end=\"367\">PLN 282,302.00<\/strong> in own contribution)<br data-start=\"388\" data-end=\"391\" \/>Funding amount: <strong data-start=\"407\" data-end=\"427\">PLN 2,072,126.75<\/strong><br data-start=\"427\" data-end=\"430\" \/>Project implementation period: <strong data-start=\"461\" data-end=\"488\" data-is-only-node=\"\">02\/01\/2020 \u2013 30\/06\/2021<\/strong><br data-start=\"488\" data-end=\"491\" \/>Principal Investigator: <strong data-start=\"515\" data-end=\"539\">Dr. Ewelina \u015awiderek<\/strong><br data-start=\"539\" data-end=\"542\" \/>\u0141ukasiewicz \u2013 PORT coordinator: <strong data-start=\"574\" data-end=\"603\">Dr. hab. Jakub Siednienko<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d96190f e-con-full e-flex e-con e-child\" data-id=\"d96190f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-177a4bb elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"177a4bb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"300\" height=\"99\" src=\"https:\/\/port.lukasiewicz.gov.pl\/wp-content\/uploads\/sites\/35\/2025\/10\/logo-ncbr-en-1.png\" class=\"attachment-full size-full wp-image-92203\" alt=\"logo ncbr en\" srcset=\"https:\/\/port.lukasiewicz.gov.pl\/wp-content\/uploads\/sites\/35\/2025\/10\/logo-ncbr-en-1.png 300w, https:\/\/port.lukasiewicz.gov.pl\/wp-content\/uploads\/sites\/35\/2025\/10\/logo-ncbr-en-1-24x8.png 24w, https:\/\/port.lukasiewicz.gov.pl\/wp-content\/uploads\/sites\/35\/2025\/10\/logo-ncbr-en-1-36x12.png 36w, https:\/\/port.lukasiewicz.gov.pl\/wp-content\/uploads\/sites\/35\/2025\/10\/logo-ncbr-en-1-48x16.png 48w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-01472b8 e-flex e-con-boxed e-con e-parent\" data-id=\"01472b8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c52861e elementor-widget elementor-widget-text-editor\" data-id=\"c52861e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"605\" data-end=\"620\"><strong data-start=\"605\" data-end=\"620\">Consortium:<\/strong><\/p><ul data-start=\"622\" data-end=\"735\"><li data-start=\"622\" data-end=\"709\"><p data-start=\"624\" data-end=\"709\"><strong data-start=\"624\" data-end=\"687\">\u0141ukasiewicz \u2013 PORT Polish Center for Technology Development<\/strong> \u2013 Consortium Leader<\/p><\/li><li data-start=\"710\" data-end=\"735\"><p data-start=\"712\" data-end=\"735\"><strong data-start=\"712\" data-end=\"735\">PURE BIOLOGICS S.A.<\/strong><\/p><\/li><\/ul><p data-start=\"737\" data-end=\"1415\">The aim of the project is to develop an innovative melanoma therapy based on an aptamer\u2013cytostatic conjugate. Standard treatments for melanoma are characterized by limited therapeutic efficacy and a high risk of adverse effects. According to the latest report by the American Cancer Society, melanoma is the fifth most commonly diagnosed cancer in the United States in both men and women. The number of diagnosed cases continues to rise each year, underscoring the strong commercial potential for a novel therapy specifically targeting cancer cells. Furthermore, the project aligns with the global trend of developing new therapeutic strategies based on carrier\u2013drug conjugates.<\/p><p data-start=\"1417\" data-end=\"1665\" data-is-last-node=\"\" data-is-only-node=\"\">Ultimately, the direct beneficiaries of the proposed solution will be melanoma patients. Introducing a new targeted therapy focusing on a molecular marker expressed on tumor cell surfaces will address a significant unmet medical need in this field.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Project funded by the National Centre for Research and Development under the Smart Growth Operational Programme 2014\u20132020 Priority Axis IV: Increasing the Scientific and Research PotentialAction 4.1: Research and DevelopmentSub-action 4.1.1: \u201cStrategic Research Programmes for the Economy\u201d Project value: PLN 2,354,428.75 (including PLN 282,302.00 in own contribution)Funding amount: PLN 2,072,126.75Project implementation period: 02\/01\/2020 \u2013 30\/06\/2021Principal [&hellip;]<\/p>\n","protected":false},"featured_media":76221,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","inline_featured_image":false,"footnotes":""},"categories":[746],"grupy_badawcze":[],"pozostale_projekty":[],"class_list":["post-93081","projects","type-projects","status-publish","format-standard","has-post-thumbnail","hentry","category-ncrd"],"acf":{"kierownik_projektu":["Dr. hab. Jakub Siednienko"],"opis_projektu":"","dofinansowanie":"Narodowe Centrum Bada\u0144 i Rozwoju","nazwa_projektu":"","tematyka_projektu":"","dofinanowanie":"National Centre for Research and Development"},"publishpress_future_action":{"enabled":false,"date":"2026-05-01 19:09:54","action":"category","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/port.lukasiewicz.gov.pl\/en\/wp-json\/wp\/v2\/projects\/93081","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/port.lukasiewicz.gov.pl\/en\/wp-json\/wp\/v2\/projects"}],"about":[{"href":"https:\/\/port.lukasiewicz.gov.pl\/en\/wp-json\/wp\/v2\/types\/projects"}],"version-history":[{"count":5,"href":"https:\/\/port.lukasiewicz.gov.pl\/en\/wp-json\/wp\/v2\/projects\/93081\/revisions"}],"predecessor-version":[{"id":95471,"href":"https:\/\/port.lukasiewicz.gov.pl\/en\/wp-json\/wp\/v2\/projects\/93081\/revisions\/95471"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/port.lukasiewicz.gov.pl\/en\/wp-json\/wp\/v2\/media\/76221"}],"wp:attachment":[{"href":"https:\/\/port.lukasiewicz.gov.pl\/en\/wp-json\/wp\/v2\/media?parent=93081"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/port.lukasiewicz.gov.pl\/en\/wp-json\/wp\/v2\/categories?post=93081"},{"taxonomy":"grupy_badawcze","embeddable":true,"href":"https:\/\/port.lukasiewicz.gov.pl\/en\/wp-json\/wp\/v2\/grupy_badawcze?post=93081"},{"taxonomy":"pozostale_projekty","embeddable":true,"href":"https:\/\/port.lukasiewicz.gov.pl\/en\/wp-json\/wp\/v2\/pozostale_projekty?post=93081"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}