Postdoc in fUS in P4Health – Center of Excellence in Precise Phenotyping and BioDataBanking for Personalised Brain Health M/K
WYMAGANIA OBOWIĄZKOWE:
- PhD in neuroscience, biomedical sciences, physics, engineering, or a related field.
- Experience with brain imaging methods (e.g functional ultrasound (fUS), fMRI; optical imaging, electrophysiology).
- Proficiency in the analysis of large-scale and complex datasets.
- Strong motivation to pursue independent research ideas in the field of psychiatric and translational neuroscience.
- Interest in investigating brain circuit function in a translational framework, linking neural activity to behavior and disease-relevant phenotypes.
- Demonstrated ability to work effectively in an international research environment.
We strongly encourage applications from candidates of all nationalities, genders, and backgrounds.
1.CV
2.Cover letter
3.Copy of PhD diploma (or thesis title and expected date of defense)
4.Contact information, including e-mail address and phone number
5.The candidates may include additional information or copies of documents/certificates in support of the application
OPIS STANOWISKA:
P4Health: Center of Excellence in Precise Phenotyping and BioDataBanking for Personalised Brain Health Project is carried out within the MAB/IRA programme of the Foundation for Polish Science.
The P4Health Centre of Excellence is an interdisciplinary initiative focused on advancing Predictive, Preventive, Personalized, and Participatory (P4) approaches in health and medicine. Within the IRAP framework, the project’s scientific goal is to discover and validate novel therapeutic concepts aimed at counteracting symptoms of brain disorders associated with astrocyte pathology. The applied research programme is designed to deliver a detailed understanding of the mechanisms of astrocyte dysfunction and its impact on neuronal networks, building on the complementary expertise of a team with a strong publication record in reputable journals and proven experience in identifying nervous system pathomechanisms and developing prototype drug candidates. Project outcomes will be protected as intellectual property and will provide a foundation for translation through clinical studies and appropriate commercialisation pathways.
P4Health’s key features:
- Interdisciplinary centre advancing P4 approaches in health and medicine
- Applied, mechanism-driven research focused on astrocyte dysfunction and its effects on neuronal networks
- Strong scientific track record demonstrated through high-quality publications and prior discoveries in nervous system pathomechanisms
- Translation-oriented strategy, from concept validation to clinical studies and commercialisation
- Systematic protection and management of intellectual property to support downstream implementation
Codzienne zadania
- Designing, conducting, and analyzing functional ultrasound (fUS) experiments in rodent models.
- Developing and pursuing an independent research project aligned with the precision psychiatry mission of P4Health.
- Analyzing and interpreting large-scale imaging and behavioral datasets.
- Integrating imaging results with translational and disease-relevant readouts.
- Actively contributing to a collaborative, interdisciplinary research environment.
- Disseminating results through high-quality publications and international conferences.
- Contributing scientifically to competitive grant proposals and, where relevant, support the research development of junior colleagues.
Oczekiwane Wyniki
Main research goals:
1. Identify and characterise key mechanisms underlying astrocyte dysfunction in brain disorders.
2. Define how astrocyte pathology reshapes neuronal networks and contributes to disease-relevant phenotypes.
3. Discover and validate novel therapeutic concepts targeting astrocyte-related mechanisms to alleviate symptoms.
The P4Health CoE is seeking a highly motivated postdoctoral researcher to conduct functional ultrasound (fUS) research on rodent models within the field of precision psychiatry. This position offers a high degree of academic freedom and is ideal for candidates who wish to shape their own research direction, build independence and contribute to the development of a centre with a strong translational mission. The position is intended for a person who has held a PhD for no longer than five years and who will participate in the project under the supervision of the Research Team Leader. The five-year period is calculated from the year in which the PhD was awarded. The start of this period is marked by the year in which the degree was obtained, and the end by the year preceding the deadline for submitting applications in the competition. The 5-year period may be extended by any documented periods of interruption in research work occurring after the date of obtaining the doctoral degree, provided that such interruptions lasted for no less than 6 months.
Benefity
- Full-time employment contract (1,0 FTE)
- Opportunity to collaborate with an experienced scientific team, with structured support for scientific and career development.
- Possibility to contribute to high-quality scientific publications and to engage in activities supporting the commercialisation of research outcomes.
- Co-financing of private medical care.
- Co-financing of a sports and wellness card.
- Option to enrol in group life insurance.
- Co-financing through the Social Benefits Fund (including holiday and Christmas benefits).
- Work in a modern, green science campus environment.
- Free on-site parking.