Process Engineer in Functional Quantitative Virology Research Group

OPIS STANOWISKA:

In this project, we aim to investigate the molecular basis of HIV-1 antisense transcripts associated with its latency. We will manipulate barcoded wildtype HIV-1 and conduct experiments using several “omics” technologies, including B-HIVE, RNA-seq, ChIP-seq, ATAC-seq, MNase-seq, HIV-1-capture HiC followed by high-throughput sequencing to characterize the molecular microenvironments of the latent HIV reservoir, especially those harboring proviruses at a deeper level of latency. Lastly, we will integrate these multidimensional datasets generated in this project to establish a deep learning-based quantitative model, enabling the prediction of the likelihood of the molecular microenvironments of the latent HIV reservoir.  The candidate will be involved in above in daily task.

CODZIENNE ZADANIA:
  • Viral manipulation, including viral transduction and transfection
  • Cell culture
  • Perform molecular biology techniques, including PCR, RT-PCR, qPCR, and prepare high-throughput sequencing libraries
  • FACS sorting
  • Participate in writing the manuscript
  • Participate lab activities (e.g., lab meeting and journal club and so on)
  • Data analysis, interpretation, visualization
  • Keeping an industry-standard work documentation.
WYMAGANIA OBOWIĄZKOWE:
  • Sc. degree (or final year of MSc studies) in biological sciences or related field supported with at least 1 year of hands-on laboratory experience.
  • Excellent interpersonal and communication skills.
  • Very good work organization and time management.
  • Experienced to work in interdisciplinary teams.
  • Conscientiousness and accuracy.
  • Professional level of English
  • Experience in cell culture.
  • Experience in molecular biology techniques (molecular cloning, PCR, RT-PCR, qPCR).
  • Enthusiastic about learning (new knowledge and techniques).
MILE WIDZIANE:
  • Experience in any “omics” approach.
  • Experience in generating high-throughput sequencing libraries.
BENEFITY:
  • Full- time employment on the position of Process Engineer
  • Scientific and organizational Support
  • Co-financing for private medical care.
  • Co-financing for a sports card.
  • Possibility to join group life insurance.
  • Co-financing under the Social Benefits Fund (for holidays and Christmas)
  • Free parking space
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