Postdoctoral Fellow in Neurodegeneration in P4Health – Center of Excellence in Precise Phenotyping and BioDataBanking for Personalized Brain Health

Essential:

• A PhD in neuroscience, cell biology, molecular biology, biomedical sciences or a related discipline or PhD dissertation due within 3 months of the application date
• Excellent skills in establishing and maintenance of cell culture
• Hands-on experience with molecular biology techniques
• Previous experience in studying neurodegeneration and/or protein quality control
• Ability to work independently and also capability of interacting within a group
• Commitment, creativity and motivation to take on challenges
• Very good work organization skills
• Excellent communication skills in English
• Comfort working in an international research environment

Desirable:

• Hands-on experience in reprogramming of human cells
• Experience with pharmacological and/or genetic approaches
• International training or work experience
• Experience with bioinformatics tools will be a plus

The P4Health Centre of Excellence is an interdisciplinary initiative focused on advancing Predictive, Preventive, Personalized, and Participatory (P4) approaches in health and medicine. Within the IRAP framework, the project’s scientific goal is to discover and validate novel therapeutic concepts aimed at counteracting symptoms of brain disorders associated with astrocyte pathology.

The applied research programme is designed to deliver a detailed understanding of the mechanisms of astrocyte dysfunction and its impact on neuronal networks, building on the complementary expertise of a team with a strong publication record in reputable journals and proven experience in identifying nervous system pathomechanisms and developing prototype drug candidates.

Project outcomes will be protected as intellectual property and will provide a foundation for translation through clinical studies and appropriate commercialisation pathways.

P4Health’s key features

• Interdisciplinary centre advancing P4 approaches in health and medicine
• Applied, mechanism-driven research focused on astrocyte dysfunction and its effects on neuronal networks
• Strong scientific track record demonstrated through high-quality publications and prior discoveries in nervous system pathomechanisms
• Translation-oriented strategy, from concept validation to clinical studies and commercialisation
• Systematic protection and management of intellectual property to support downstream implementation

Main research goals

P4Health CoE is seeking a highly motivated Postdoctoral Researcher to conduct functional ultrasound (fUS) studies in rodent models within the framework of precision psychiatry. This position offers a high degree of scientific freedom and is ideally suited for candidates who wish to shape their own research focus, build independence, and contribute to a growing center with a strong translational mission.

The position is intended for a person who has held a doctoral degree for no longer than 5 years and who participates in the implementation of the Project under the supervision of the Research Team Leader. The 5-year period is counted from the year in which the doctoral degree was obtained. The beginning of this period is marked by the date of obtaining the degree, and the end by the year preceding the deadline for submitting applications in the competition. The 5-year period may be extended by all documented periods of interruption in scientific work occurring after the date of obtaining the degree, with interruptions lasting at least 6 months being taken into account

We strongly encourage applications from candidates of all nationalities, genders, and backgrounds.