A position is available in the Research Group Quantitative Virology at Łukasiewicz-PORT. We are looking for a highly enthusiastic person to strengthen our interdisciplinary team in exciting research combining state-of-the-art genetic approaches with advanced molecular and physiological readouts. In this project, we aim to investigate the molecular basis of HIV-1 antisense transcripts associated with its latency. We will manipulate barcoded wildtype HIV-1 and conduct experiments using several “omics” technologies, including B-HIVE, RNA-seq, ChIP-seq, ATAC-seq, MNase-seq, HIV-1-capture HiC followed by high-throughput sequencing to characterize the molecular microenvironments of the latent HIV reservoir, especially those harboring proviruses at a deeper level of latency. Lastly, we will integrate these multidimensional datasets generated in this project to establish a deep learning-based quantitative model, enabling the prediction of the likelihood of the molecular microenvironments of the latent HIV reservoir.
Expectations:
- M.Sc. degree (or final year of MSc studies) in biological sciences or related field supported with at least 1 year of hands-on laboratory experience.
- Excellent interpersonal and communication skills.
- Very good work organization and time management.
- Experienced to work in interdisciplinary teams.
- Conscientiousness and accuracy.
- Professional level of English.
- Experience in cell culture.
- Experience in molecular biology techniques (molecular cloning, PCR, RT-PCR, qPCR).
- Enthusiastic about learning (new knowledge and techniques).