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Job Offers at Łukasiewicz – PORT
Below you will find our current job openings, which include both research positions and support roles. Select the area that interests you, find a role that matches your skills, and join the Łukasiewicz team.
Don’t see a position that fits you? Send us your CV at rekrutacja@port.lukasiewicz.gov.pl – we will contact you if a role matching your profile becomes available.
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- PhD in Neuroscience, Neurobiology, Physiology, Biomedical Engineering or a related discipline.
- Excellent spoken and written English.
- Proven experience working with laboratory mice.
- Experience in rodent surgery and regulated animal procedures.
- Experience with behavioural assays in rodents.
- Strong organisational skills and ability to work independently.
- Willingness to travel and present research internationally.
- Experience with neuropathic pain models.
- Experience with in vivofunctional imaging (especially one- or two-photon calcium imaging).
- Experience with viral vectors (AAV) and stereotaxic or neonatal injections.
- Experience with image analysis and quantitative data analysis (Python, MATLAB or R).
- Experience with computational analysis of large biological datasets.
You will join the international consortium “DECIPHER: Deciphering the role of CD90+ stromal cells in neuropathic pain”, funded under the ERA-NET programme. The consortium aims to uncover the cellular and molecular mechanisms underlying chronic neuropathic pain and to establish the foundations for novel targeted analgesic therapies. The project is based on the hypothesis that CD90+ stromal cells play a central role in driving and maintaining peripheral sensory neuron hyperexcitability, thereby contributing to persistent neuropathic pain independently of classical inflammation. Your work will focus on the preclinical validation of newly identified therapeutic targets using complementary mouse models of neuropathic pain, integrating behavioural neuroscience with advanced in vivo neurophysiology (pharmacological interventions and functional calcium imaging and multi-electrode arrays, MEA).
You will specialise in advanced in vivo neurophysiology, combining behavioural neuroscience with functional optical imaging of sensory neurons. Using viral delivery of genetically encoded calcium indicators (AAV9-GCaMP6s), you will perform large-scale in vivo calcium imaging of dorsal root ganglion (L3/L4 DRG) neurons together with quantitative behavioural assessment of neuropathic pain. The project combines state-of-the-art optical imaging, pharmacological intervention, computational data analysis and translational neuroscience in close collaboration with leading European laboratories.
The successful candidate will be employed full-time for 36 months within an internationally funded collaborative project and will have the opportunity to work with leading European groups in translational pain neuroscience while developing expertise in advanced systems neuroscience and preclinical therapeutic validation.
You will be responsible for the experimental implementation of the preclinical work package (WP3). Your responsibilities will include:
- performing regulated animal procedures and inducing mouse models of neuropathic pain,
- carrying out behavioural phenotyping (mechanical and thermal hypersensitivity assays together with automated home-ge monitoring),
- performing terminal in vivocalcium imaging experiments from dorsal root ganglion neurons,
- administering and evaluating novel therapeutic compounds, including monoclonal antibodies and receptor ligands,
- analysing large-scale neuronal population imaging datasets using computational pipelines,
- maintaining high-quality experimental documentation and metadata,
- presenting results during consortium meetings and international conferences,
- contributing to manuscript preparation and dissemination of project results.
· Co-financing of private medical care.
· Co-financing of a sports and wellness card.
· Option to enrol in group life insurance.
· Co-financing through the Social Benefits Fund (including holiday and Christmas benefits).
· Work in a modern, green science campus environment.
· Free on-site parking.
- Holds or be near completion of PhD in Neuroscience or related discipline (i.e. Neurobiology, Biophysics, etc.),
- Advanced spoken and written English skills,
- Proven research track record,
- Ability to travel and present data internationally,
- Ability to plan your own work and/or the work of the person you line manage (i.e. PhD students),
- Documented work experience with mouse models >1 year (i.e. behavioural tests on mice),
- Good understanding of molecular genetics and viral vectors,
- Good analytical skills.
- Experience with pain models,
- Experience in animal surgery (stereotaxic injections),
- Experience in mouse behavioural assays (affective, locomotor and nociceptive thresholds assessment, preferably with computer vision tools),
- Experience in neurophysiological techniques, especially in vivo functional optical imaging (1-/2- photon)
- Coding skills, or ability to implement written scripts in R/Python/Matlab for data analysis.
The role:
You will work on a generously funded project that delves into presynaptic control of primary sensory neurons by top-down brainstem noradrenergic neurons. You will use novel sensory neuron type specific alpha-2c-adrenoceptor knock-out mice in conjunction with selective optogenetic modulation of the top-down noradrenergic circuits to probe the noradrenergic mechanisms controlling nociception.
You will be specialising in in-depth histological and functional analysis of the knock-out mouse model. An ideal candidate will have a background in transgenic animals work and cutting-edge histological approaches (incl. RNAscope, tissue clearing and expansion microscopy apart from classic immunohistochemistry) with contemporary computational approaches in image analysis. A strong drive to learn and perform in vivo neurophysiological techniques (such as one and 2-photon in vivo calcium imaging) as well as rodent nociceptive behavioural testing will be of advantage
You will be specialising in in-depth histological and functional analysis of the knock-out mouse model. An ideal candidate will have a background in transgenic animals work and cutting-edge histological approaches (incl. RNAscope, tissue clearing and expansion microscopy apart from classic immunohistochemistry) with contemporary computational approaches in image analysis. A strong drive to learn and perform in vivo neurophysiological techniques (such as one and 2-photon in vivo calcium imaging) as well as rodent nociceptive behavioural testing will be of advantage.
Your main duties:
- you will be to perform in-depth tissue analysis post-mortem.
- You will supervise correct transgenic animal lines breeding (in continuous cooperation with the lab technician) and take responsibility for regulated animal procedures.
- You will ensure that data (and associated metadata) are of the highest quality and in a form that allows for further processing.
You will be asked to:
- independently undertake the research project, and execute experiments in consultation with the group leader,
- participate in lab activities, including group meetings, journal clubs, seminars and conferences,
- write up findings for publications and completing revisions, iv) collaborate with other lab members on daily lab work.
· Co-financing of private medical care.
· Co-financing of a sports and wellness card.
· Option to enrol in group life insurance.
· Co-financing through the Social Benefits Fund (including holiday and Christmas benefits).
· Work in a modern, green science campus environment.
· Free on-site parking.
-Ph.D. in computational science, mathematics, physics or relevant fields.
-At least one first-author peer-reviewed research article.
-Working knowledge of Python; knowing additional programming languages (e.g., R) will be appreciated.
-Anticipating projects related to constructing deep learning-based models and in silico modeling with metagenomics datasets or with population genetics datasets.
-Task-oriented person and a team worker.
-Good communication skills in English (written and spoken).
The candidate must meet the requirements of the NCN project Regulations, in particular by obtaining their doctoral degree in the year of employment in the project or within 7 years prior to 1 January of the year of employment in the project.
This period may be extended by the time spent during that interval on long-term (over 90 days) documented sick leave or on rehabilitation benefits due to incapacity for work. Additionally, it may be extended by the number of months spent on childcare-related leave granted under the Labour Code. In the case of women, this period may also be extended by 18 months for each child born or adopted, if this method of accounting for breaks in the academic career is more favourable.
For more information check: https://ncn.gov.pl/sites/default/files/pliki/uchwaly-rady/2022/uchwala60_2022-zal1.pdf#page=52
The successful applicant will work in an established laboratory and join a collaborative, vibrant, and growing community of researchers in an environment that values creativity and scientific communications in Łukasiewicz–PORT. In our team, we carry on both wet-lab experiments and dry lab bioinformatics analyses. The candidate will join scientific discussions with other team members. Together with the team leader, the candidate will help with training newcomers. Overall, the candidate will have a great opportunity to participate in research on training and gain knowledge and skills for his/her career development. This position offers the potential for contract extension.
job description
The Quantitative Virology Research Group in Łukasiewicz–PORT invites applications for a postdoctoral position starting as soon as possible. We are recruiting applicants with broad research interests to work on Big Data, multigenomic studies, and computational modeling.
The candidate will join ongoing projects in our team and perform mathematical/computational modeling. The topics include (1) constructing deep learning-based models to predict the molecular microenvironments of the latent HIV reservoir and (2) profiling the landscapes of enriched antisense RNA k-mers across HIV-1 subtypes.
Our laboratory has proposed the presence of distinct molecular microenvironments in the latent HiV reservoir (Chen H. 2026. J Virol 100:e00175-26), which leads to the heterogeneous nature of the reservoir configuration. The candidate will apply an array of “omics” datasets generated in the lab to construct deep learning-based models, enabling the classification and prediction of distinct microenvironments and seek critical predictor attributes in defining distinct microenvironments.
In addition, our lab previously established the streamlined pipeline named the Pathogen Origin Recognition Tool using Enriched K-mers (PORT-EK) (https://github.com/Quantitative-Virology-Research-Group/PORT-EK-version-2), which is a k-mer-based approach, facilitating the comparison of various multigenomic datasets and detecting over-represented genomic regions (i.e., k-mers) linked to specific sequences (Wiśniewski and Chen 2025 IMetaOmics PMID: 41675161; Wiśniewski et al. 2026 BioRxiv DOI:10.64898/2026.02.25.707904). The candidate will further reinforce the pipeline to identify enriched k-mers using HIV-1 antisense transcripts across subtypes. In parallel, the candidate will work on exploring epidemiological models within the framework of phylodynamics and phylogeography and integrating them with population genetics models. Increasing the performance of integration algorithms and model simulations, and developing machine learning methods for analyzing genomic data.
Computational/mathematical modeling and bioinformatic analysis
- Full-time employment on the position of Senior Specialist.
- Work in a scientific research organization focused on the implementation of innovative R&D projects.
- Co-financing for private medical care.
- Co-financing for a sports card.
- Possibility to join group life insurance.
- Co-financing under the Social Benefits Fund (for holidays and Christmas).
- Work on the territory of a green science campus.
- Free parking space.
- Additional 10 days of paid leave per year for employees of the research division.
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