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Oferty pracy w Łukasiewicz - PORT
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Znajdź stanowisko dla siebie
Filtry
• a PhD in biology, biotechnology, medical biology, neurobiology or a related field;
• experience in conducting research using animal models;
• practical knowledge of stereotactic techniques and behavioural analysis;
• experience in working with molecular biology and biochemistry methods;
• experience in analysing and interpreting experimental data;
• ability to plan and carry out experiments independently;
• experience in preparing scientific publications and grant applications;
• good command of spoken and written English.
• experience in the design and production of viral vectors;
• experience in research in the field of neurobiology or neurodegenerative diseases;
• experience in developing research protocols and quality documentation.
The Senior Research Engineer at the P4Health Centre of Excellence, funded under the Horizon Europe Teaming for Excellence programme, will be responsible for planning and carrying out advanced preclinical research using animal models and state-of-the-art methods in molecular biology, biochemistry and neurobiology. The successful candidate will work within Technology Platform 3, supporting the implementation of research projects conducted as part of the P4Health scientific agenda and the development of the platform’s research infrastructure and expertise.
Key responsibilities in this role will include designing and conducting experiments using animal models, producing and applying viral vectors, carrying out molecular and biochemical analyses, and compiling and interpreting research results. The person in this role will also participate in the development, implementation and refinement of standard operating procedures (SOPs) for research methods developed and used within Technology Platform 3.
- planning research activities and preparing documentation required to obtain approvals for experiments involving laboratory animals (mice);
- conducting in vivo experiments, including stereotactic surgeries, behavioural analyses, and collection and isolation of biological material;
- designing, producing, and validating viral vectors for preclinical research applications;
- performing molecular and biochemical analyses using techniques such as qPCR, Western blot, ELISA, immunohistochemistry, and immunofluorescence;
- preparing samples for proteomic and metabolomic analyses;
- performing statistical analyses of experimental data and interpreting research results;
- preparing reports, presentations, and materials for scientific publications and research projects;
- contributing to the development, validation, and implementation of Standard Operating Procedures (SOPs) for methods used within Technology Platform 3;
- participating in the development and optimization of research methodologies and the implementation of new experimental technologies;
- collaborating with P4Health research groups, other Technological Platforms and project partners in the execution of research activities and knowledge transfer.
- Co-financing of private medical care
- Co-financing of a sports and wellness card
- Option to enroll in group life insurance
- Benefits co-funded through the Social Benefits Fund (including holiday and Christmas benefits)
- Work in a modern, green science campus environment
- Free on-site parking
-Ph.D. in computational science, mathematics, physics or relevant fields.
-At least one first-author peer-reviewed research article.
-Working knowledge of Python; knowing additional programming languages (e.g., R) will be appreciated.
-Anticipating projects related to constructing deep learning-based models and in silico modeling with metagenomics datasets or with population genetics datasets.
-Task-oriented person and a team worker.
-Good communication skills in English (written and spoken).
The candidate must meet the requirements of the NCN project Regulations, in particular by obtaining their doctoral degree in the year of employment in the project or within 7 years prior to 1 January of the year of employment in the project.
This period may be extended by the time spent during that interval on long-term (over 90 days) documented sick leave or on rehabilitation benefits due to incapacity for work. Additionally, it may be extended by the number of months spent on childcare-related leave granted under the Labour Code. In the case of women, this period may also be extended by 18 months for each child born or adopted, if this method of accounting for breaks in the academic career is more favourable.
For more information check: https://ncn.gov.pl/sites/default/files/pliki/uchwaly-rady/2022/uchwala60_2022-zal1.pdf#page=52
The successful applicant will work in an established laboratory and join a collaborative, vibrant, and growing community of researchers in an environment that values creativity and scientific communications in Łukasiewicz–PORT. In our team, we carry on both wet-lab experiments and dry lab bioinformatics analyses. The candidate will join scientific discussions with other team members. Together with the team leader, the candidate will help with training newcomers. Overall, the candidate will have a great opportunity to participate in research on training and gain knowledge and skills for his/her career development. This position offers the potential for contract extension.
job description
The Quantitative Virology Research Group in Łukasiewicz–PORT invites applications for a postdoctoral position starting as soon as possible. We are recruiting applicants with broad research interests to work on Big Data, multigenomic studies, and computational modeling.
The candidate will join ongoing projects in our team and perform mathematical/computational modeling. The topics include (1) constructing deep learning-based models to predict the molecular microenvironments of the latent HIV reservoir and (2) profiling the landscapes of enriched antisense RNA k-mers across HIV-1 subtypes.
Our laboratory has proposed the presence of distinct molecular microenvironments in the latent HiV reservoir (Chen H. 2026. J Virol 100:e00175-26), which leads to the heterogeneous nature of the reservoir configuration. The candidate will apply an array of “omics” datasets generated in the lab to construct deep learning-based models, enabling the classification and prediction of distinct microenvironments and seek critical predictor attributes in defining distinct microenvironments.
In addition, our lab previously established the streamlined pipeline named the Pathogen Origin Recognition Tool using Enriched K-mers (PORT-EK) (https://github.com/Quantitative-Virology-Research-Group/PORT-EK-version-2), which is a k-mer-based approach, facilitating the comparison of various multigenomic datasets and detecting over-represented genomic regions (i.e., k-mers) linked to specific sequences (Wiśniewski and Chen 2025 IMetaOmics PMID: 41675161; Wiśniewski et al. 2026 BioRxiv DOI:10.64898/2026.02.25.707904). The candidate will further reinforce the pipeline to identify enriched k-mers using HIV-1 antisense transcripts across subtypes. In parallel, the candidate will work on exploring epidemiological models within the framework of phylodynamics and phylogeography and integrating them with population genetics models. Increasing the performance of integration algorithms and model simulations, and developing machine learning methods for analyzing genomic data.
Computational/mathematical modeling and bioinformatic analysis
- Full-time employment on the position of Senior Specialist.
- Work in a scientific research organization focused on the implementation of innovative R&D projects.
- Training in the use of modern techniques, including work with conditional knockout mice for tissue-specific deletion, complex biochemistry, protein complex purification, and in vivo confocal imaging.
- Co-financing for private medical care.
- Co-financing for a sports card.
- Possibility to join group life insurance.
- Co-financing under the Social Benefits Fund (for holidays and Christmas).
- Work on the territory of a green science campus.
- Free parking space.
- Additional 10 days of paid leave per year for employees of the research division holding the title PhD.
Specjalista – Inżynier Procesu w Grupie Badawczej Synaptogenezy (k/m) – drugi wakat
2 dni do wygaśnięcia Wrocław- wykształcenie wyższe w dziedzinie biologii molekularnej lub pokrewnej
- znajomość techniki pcr oraz elektroforezy dna będzie dodatkowym atutem
- bardzo dobra organizacja pracy
- dokładność i sumienność w pracy
- komunikatywność
- dobra znajomość języka angielskiego
- doświadczenie w pracy laboratoryjnej
Osoba zatrudniona na tym stanowisku będzie odpowiadała za kompleksowe wsparcie organizacyjne, logistyczne i administracyjne Grupy Badawczej Synaptogenezy.
- przygotowywanie zamówień na odczynniki i sprzęt zgodnie z prawem zamówień publicznych
- kontrola i weryfikowanie budżetu laboratorium
- dbanie o czystość i bezpieczeństwo pracy w laboratorium badawczym
- logistyka i organizacja pracy w laboratorium badawczym
- dbanie o porządek organizacyjny w laboratorium
- genotypowanie myszy przy użyciu techniki PCR
- prowadzenie ewidencji kolekcji myszy transgenicznych
- zatrudnienie na umowę o pracę na czas określony na pełen etat stanowisku Specjalista
- możliwość pracy w nowoczesnym laboratorium z dostępem do najnowszej infrastruktury badawczej
- dofinansowanie do prywatnej opieki medycznej
- dofinansowanie do karty sportowej
- możliwość dołączenia do grupowego ubezpieczenia na życie
- dofinansowania w ramach ZFŚS (do wypoczynku oraz Świąt Bożego Narodzenia)
- bezpłatne miejsce parkingowe
- program rekomendacji pracowniczych
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