Comprehensive production of monoclonal and polyclonal antibodies

Technologies

Comprehensive production of monoclonal and polyclonal antibodies

Antibodies

Bioengineering Research Group operating within Łukasiewicz – PORT, offers comprehensive services for obtaining high-quality antibodies – both monoclonaland polyclonal – tailored to a wide range of research and industrial applications.

Experienced team and advanced technological facilities

Thanks to many years of experience and state-of-the-art research infrastructure, we offer:

  • Production of mouse monoclonal antibodies on a scale of up to several grams.
  • Manufacturing of polyclonal sera with high specificity.
  • Preparation of conjugates suitable even for weakly immunogenic antigens and haptens.

Our technologies enable efficient production of antibodies with a high degree of purity and fully aligned with application requirements.

Scope of specialized services

The offer includes a broad spectrum of activities:

  • Preparation and characterization of antigens (proteins, bacterial polysaccharides, LPS, and others).
  • Development of hybridoma cell lines producing monoclonal antibodies.
  • Purification and production of antibodies directed against various antigens.
  • Design of conjugates, including:

    • Fluorescent labels,
    • Nanoparticles,
    • Protein carriers, polymer carriers, and others.
  • Immobilization of biological particles on various substrates, such as glass, polymer nanoparticles, or other nanostructured materials.
  • Validation of antibodies for specific applications.
    • Western Blot,
    • ELISA,
    • Flow cytometry,
    • Immunohistochemistry (IHC).
  • Advanced antigen–antibody interaction analysis: kinetics, dissociation constants, and other parameters.

Applications and collaboration opportunities

Antibodies developed at Łukasiewicz – PORT are used in:

  • Laboratory diagnostics,


  • In immunohistochemical and fluorescence staining,
  • In flow cytometry,
  • In biosensors and detection systems.

Collaboration with industry and the academic community

The team carries out numerous research and implementation projects in cooperation with partners from the science and industry sectors, both in Poland and abroad. We provide expert support for projects based on the use of antibodies – from concept development, through research, to final application.


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