Rozwój opatrunków perowskitowych emitujących światłodo przyspieszonego gojenia ran

Projekt finansowany przez Narodowe Centrum Nauki w ramach konkursu „POLONEZ BIS 2”.

Nr projektu: UMO-2022/45/P/ST3/04170
Wartość projektu: 1.117.080,00 PLN
Wartość dofinansowania: 1.117.080,00 PLN
Okres realizacji projektu: 01.04.2022 – 01.05.2025

Kierownik projektu: dr Somnath Mahato

When someone does small changes in a material synthesize, big changes in its physical properties such as structural, optical and electrical etc. can occur. So small changes in material synthesis can lead to big changes in an optoelectronic device performance. Recently, halide perovskite commercial products nanocrystals (NCs) synthesized by conventional hot injection show exciting potential for optoelectronic applications, especially for light-emitting devices (LEDs), owing to their intrinsically high photoluminescence quantum efficiency (PLQE) and color purity and color tunability. With efforts made over the last 5 years, the external quantum efficiency (EQE) of halide perovskite-based LEDs has sharply increased beyond 20%, which is comparable to the performance of existing lighting technology. However, synthesize of stable, phase-pure, mono-dispersed halide perovskite NCs by conventional hot-injection approach is still challenging due to the fast reaction kinetics and unrevealed ligand chemistry. Therefore, goal of the project is to synthesize of highly air stable, single crystalline, mono-dispersed, phase-pure halide perovskite [CsPbX3 (X = Cl, Br & I)] nanocrystals by modified hot injection method. A passivation process of the halide perovskite NCs will enhance the air stability of the NCs by using a functional ligand (1-dodecanethiol or 1-octadecanethiol) and B-site doping (Cu++ doping) for the first time which significantly reduce the surface states, increase vacancy formation energy, higher photoluminescence quantum yields, and much improve air stability. Utilizing the superior PLQE, high color purity and color tunability of the halide perovskite NCs, the project will develop perovskite light emitting electrochemical cells (PeLECs) on a flexible platform for wound healing. The fabricated PeLECs will emit different colors (red, green and blue) based on the perovskite active layer at a visible wavelength spectrum and intensity close to mimic natural sunlight. The intensity of light will increase using an electron transport layer (ETL) or hole transport layer (HTL). Also, this project will investigate the effects of red, blue, and green color PeLECs for wound healing. Light exposure in the red part of the spectrum (620-750 nm) induces growth of keratinocytes and fibroblasts in deeper layers of the skin. The green part of the spectrum (500-565 nm) promotes wound healing by inducing migratory and proliferative mediators, which will be a new powerful therapeutic strategy for wound healing. The blue part of the spectrum (450–495 nm) is known to have antibacterial effects predominantly at the surface layers of the skin. In order to succeed the proposal, the system will consist of three parts: (1) Synthesis of halide perovskite NCs by modified hot-injection method (2) Fabrications and characterizations of flexible PeLECs and optimizing PEDOT:PSS as a HTL and zinc oxide as an ETL for the improvement of PLQE and EQE of the flexible devices and (3) Application of light-based treatments in enhancing various aspects of wound healing, examine the drawbacks that will improve the translation of some light-based therapies into clinical use, which benefits over current standards in wound care.